Endocrine Abstracts

We use redundant peptide counting as a tool to compare, quantitatively, data from mass spectrometry analyses. When combined with hierarchical clustering, a tool commonly used for micro array analysis, we can group proteins based on their relative abundance across samples. In this way, we recently completed a spatial map of the secretory pathway of rat hepatic cells comprising some 1400 different proteins, each with a defined distribution (Gilchrist, Au, Hiding et al. 20...